# Gene view / LoF burden

![](https://1223477342-files.gitbook.io/~/files/v0/b/gitbook-legacy-files/o/assets%2F-LvPur3Kbj-JuAmvOiI6%2F-LxM7kssA_MstvsaY1q7%2F-LxM8oeBwZtXEWbvkV4c%2Fscreenshot_lof_anno.png?alt=media\&token=bc89afce-6330-4258-8814-2d676304cb67)

**Clicking on any gene** will bring you to the **gene view** with association results for that gene region, the loss-of-function analysis results (for methods see [LoF burden](../methods/lof-burden)) and an annotated list of all loss of function and missense variants.&#x20;

### LoF burden results

| Column                                                   | Description                                                                                           |
| -------------------------------------------------------- | ----------------------------------------------------------------------------------------------------- |
| <p><strong>p-value</strong><br><strong>beta</strong></p> | P-value and beta from [association test](../../methods/phewas/logistic-regression#association-tests). |
| **variants**                                             | All LoF variants within that gene.                                                                    |

