FinnGen Spin Offs

FinnGen spin offs are separate studies that fall outside the scope of the Research Project FinnGen but are conducted by FinnGen Partners and have separate research permits and decisions of approval of the respective biobank(s) and Finnish national registries (if register data is used in the study).

These can for example, include recall of the biobank study subjects (same study subjects that participated in FinnGen) for new samples, based on their genotype carrier statuses or deeper investigation of hospital pathology and imaging data.

Time to time FinBB or any one FinnGen Partner biobank can ask FinnGen to perform search of FinnGen study subjects for possible Spin Offs. For launching such search, FinBB (or any other FinnGen Partner biobank) needs to fill in the Spin Off feasibility form:

Here's how the process works:

1. FINBB or any given FinnGen Partner biobank fills out the Spin Off Feasibility e-form.

2. The form is automatically directed to FinnGen's Data Protection Officer (DPO), admins, and data managers. The DPO checks if the request is okay and if there's enough information to proceed.

3. Once approved by the DPO, the FinnGen Partner Researcher passes list(s) of potential FinnGen Spin Off participants to finngen/red bucket in Sandbox and informs [e-mail] names and location of the list(s).

Please note:

• The list(s) should be named as follows: $spin-off-project-id_$biobank_name_$list_name.txt, eg. BB_2017-PP_TAMPERE_FG_IDS.txt

• The list(s) should only contain FinnGen IDs. If other data is requested (no registry data is allowed), they should be described in the original spin off feasibility e-form.

• Separate list(s) should be generated per each biobank.

• FinnGen’s embargo period should be taken into account and the list(s) should only include individuals whose genotype data is already available at the biobank(s)

4. The FinnGen data manager passes the list(s) to the biobank(s)

For more information, please contact FINBB ([e-mail]) or FinnGen admin team ([e-mail])