Finnish Registry for Kidney Diseases

Sandbox directory

The data is available in the following Sandbox directory:

/finngen/library-red/finngen_R[RELEASE]/kidney_disease_register_1.0

Please refer to the readme file in the sandbox directory for full details of the available data.

Note, this data also available in Atlas and OMOP common data model.

Description

The Finnish Registry for Kidney Diseases has comprehensive coverage of dialysis and kidney transplantation patients in Finland. FinnGen data consists of FinnGen participants with dialysis from kidney transplants in Finland since 1964.

Variables

Diagnoses behind kidney diseases (finngen_R12_kidney_disease_register):

FINNGENID	Study id
EVENT_AGE	Age at the time of the event (some kidney disease)
KIDNEYREG_T1DM	Type 1 diabetes with a causal role to some kidney disease. E10
KIDNEYREG_T2DM	Type 2 diabetes with a causal role to some kidney disease. E11
KIDNEYREG_POLYCYS	Polycystic kidney disease. Q61[1-3]
KIDNEYREG_GLOMNEPH	Glomerulonephritis. NO[0|1|3]
KIDNEYREG_NEPHROSCLER	Nephrosclerosis. 112|113|1701|N280
KIDNEYREG TUBULOINT	Tubulointerstitial nephritis. N1[0-2]
KIDNEYREG_AMYLOIDOSIS	Amyloidosis. E85
KIDNEYREG_ACTIVE	Active kidney disease therapy = All patients in the kidney disease register data.

Kidney disease register, Incidence (finngen_R12_kidney_disease_register_incidence):

FINNGENID	Study id
EVENT_AGE	Age at the time of event (Start of active treatment)
APPROX_EVENT_DAY	Date of the event (+/- 15 days)
START_YEAR	Year of the start of active treatment
KIDNEY_DISEASE_DIAGNOSIS_1	Diagnosis 1
KIDNEY_DISEASE_DIAGNOSIS_2	Diagnosis 2
ERA_EDTA_DIAGNOSIS	ERA EDTA Diagnosis
EDTA_DIAGNOSIS_OLD	Old EDTA Diagnosis
APPROX_END_DATE_OF_TRACKING	Date of end of tracking (+/-15 days). This variable contained whole numbers. Those were transformed to date using 1899-12-30 as origin (excel).
END_OF_TRACKING_AGE	Age at the time of end of tracking
HEIGHT	Height
WEIGHT	Weight
SYSTOLIC_BLOOD_PRESSURE	Systolic blood pressure
DIASTOLIC_BLOOD_PRESSURE	Diastolic blood pressure
CHOLESTEROL	Cholesterol
HDL_CHOLESTEROL	HDL cholesterol
TRIGLYCERIDE	Triglycerides
PREVIOUS	Previous smoker (0=No, 1=Yes)
CURRENT	Current smoker (0=No, 1=Yes)
APPROX_START_DATE_OF_NERF_TRACKING	Start date of nerf tracking
START_OF_NERF_TRACKING_AGE	Age at the time of nerf tracking
ANGINA_PECTORIS	Angina pectoris (0=No, 1=Yes)
HEART_ATTACK	Heart attack (0=No, 1=Yes)
BYPASS_OR_OTHER_PROCEDURE	Bypass or other procedure (0=No, 1=Yes)
LEFT_VENTRICULAR_HYPERTROPHY	Left venticular hypertrophy (0=No, 1=Yes)
HEART_FAILURE	Heart failure (0=No, 1=Yes)
OTHER_VASCULAR_DISEASE	Other vascular disease (0=No, 1=Yes)
OTHER_VASCULAR_DISEASE_ENTRY	Other vascular disease entry (0=No, 1=Yes)
OTHER_VASCULAR_DISEASE_AMPUTATION	Other vascular disease amputation (0=No, 1=Yes)
DYSLIPIDEMIA_DIET_TREATMENT	Dyslipidemia diet treatment (0=No, 1=Yes)
DYSLIPIDEMIA_MEDICAL_TREATMENT	Dyslipidemia medical treatment (0=No, 1=Yes)
STROKE	Stroke (0=No, 1=Yes)
RR_MEDICAL_TREATMENT	RR medical treatment (0=No, 1=Yes)
T1D	Type 1 diabetes (0=No, 1=Yes)
T2D	Type 2 diabetes (0=No, 1=Yes)
UNKNOWN_TYPE_OF_DIABETES	Unknown type of diabetes (0=No, 1=Yes)
IV_IRON	IV Iron (0=No, 1=Yes)
VITAMIN_D_TREATMENT	Vitamin d treatment (0=No, 1=Yes)
EPO_TREATMENT	EPO treatment (0=No, 1=Yes)
FISTULA_IN_FIRST_DIALYSIS_TREATMENT	Fistula in first dialysis treatment (1=Fistula, 2=Tunneled catheter, 3=Temporary catheter, 4=Graft)
APPROX_DATE_OF_DISCOVERING_DIABETES	Date of discovering diabetes (+/- 15 days)
DISCOVERING_DIABETES_AGE	Age at the time of discovering diabetes
REASON_FOR_TERMINATION_OF_ACTIVE_TREATMENT	Reason for termination of active treatment (Alive in treatment, Treatment terminated, uremic, Died during treatment, Own kidney function, treatment < 3 months, Own kidney function, treatment > 3 months)

Kidney disease register, Prevalence (finngen_R12_kidney_disease_register_prevalence):

FINNGENID	Study id
YEAR	Year
FISTULA	Fistula (1=Fistula, 2=Graft, 3=Katheter)
ANTIHYPERTENSIVE_DRUG	Antihypertensive drug (0=No, 1=Yes)
ESA_TREATMENT	ESA treatment (0=No, 1=Yes)
IV_IRON	IV iron (0=No ,1=Yes)
DIALYSIS_PER_WEEK	Number of dialysis treatments per week
DIALYSIS_H_PER_WEEK	Dialysis treatment time in hours per week
AZATHIOPRINE	Azatioprine (0=No, 1=Yes)
CICLOSPORIN	Ciclosporin (0=No, 1=Yes)
TACROLIMUS	Tacrolimus (0=No, 1=Yes)
MYCOPHENOLATE	Mycophenolate (0=No, 1=Yes)
STEROIDS	Streroids (0=No, 1=Yes)
OTHER_IMMUNOSUPPRESSIVE	Other immunosuppressive medication (0=No, 1=Yes)
ON_TRANSFER_LIST_OR_NOT	On transfer list or not (0=No, 1=Yes)
PRODUCTION_OF_URINE	Production of urine
PERITONITIS_PER_YEAR	Number of peritonitis per year
T1D	Type 1 diabetes (0=No, 1=Yes)
T2D	Type 2 diabetes (0=No, 2=Yes)
UNKNOWN_TYPE_OF_DIABETES	Unknown type of diabetes (0=No, 3=Yes)
DIABETES_AGE	Age at diabetes diagnosis
APPROX_DIABETES_DATE	Date of diabetes diagnosis (+/- 15 days)

Kidney disease register, Treatment history (finngen_R12_kidney_disease_register_treatment_history):

FINNGENID	Study id
EVENT_AGE	Age at the time of event (treatment change)
APPROX_EVENT_DAY	Approximated date of treatment change (+/-15 days)
PREVIOUS_FORM_OF_TREATMENT	Previous form of treatment (*listed below)
CURRENT_FORM_OF_TREATMENT	Current form of treatment (*listed below)
TYPE_OF_CHANGE	Categorical type of change (T=Change in the form of treatment, H= Change of hospital, D=Death, NA=New patient)

More information about the data is available from the Finnish Registry for Kidney Diseases.