Pairwise endpoint genetic correlation format
This pipeline produces a single file, containing all pairwise genetic correlations between multiple phenotypes.
Its name is structured as finngen_R[?]_[EUR/FIN].ldsc.summary.tsv
where EUR/FIN changes based on the LD panel used.
(This refers to genetic correlation, in Risteys you can also see the number of shared cases between endpoints.)
Column name
Description
p1
Phenotype 1
p2
Phenotype 2
rg
Genetic correlation
se
Standard error
z
z-score
p
pvalue
h2_obs
heritabilty of p1
h2_obs_se
SE of heritability of p1
h2_int
heritability intercept for p1
h2_int_se
SE of intercept
gcov_int
intercept of genetic covariance
gcov_int_se
SE of gcov
CONVERGED
A flag if the LDSC model converged
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