Cohort Summary Statistics in Atlas

The Atlas Characterizations allow you to create cohort-level descriptive summary statistics. You can use these statistics to review the conditions, medications, age, sex, and demographics of your cohorts before using them in analyses. They may help you to make sure that your cohorts have expected characteristics while not having any unexpected or unwanted features.

The Characterizations use standard codes. If you are using non-standard codes you must first find equivalent standard codes.

In this tutorial, we will use Characterizations to compare case and control cohorts for excessive earwax.

Create a new Characterization

Choose the Characterizations option from the left menu
Click the New Characterization button on the top right

We have named the Characterization as ExcessiveEerwax:

Import Cohorts

First, click the Import button below the Cohort definitions to select your cohorts.

We have filtered the cohorts using ExcessiveEerwax and selected our case and control cohorts:

Click the Import button at the bottom right to select these two cohorts.

The two imported cohorts are shown below the Cohort definitions:

Import Features

Next, click the Import button below the Feature analyses to select the features for the summary statistics:

We have filtered the features by selecting the DEMOGRAPHICS Domain and selected the Demographics Age and Demographics Gender features:

Click the Import button at the bottom right to select these two features.

The two imported features are shown below the Feature analyses:

Save the Characterization

Save your Characterization by clicking the button on the right side of its name.

Create summary statistics

Open the Executions tab
Click the Generate button on the right side of a FinnGen data release. The summary statistics will be created for this FinnGen data release.

The Characterization must be saved before summary statistics can be generated.

Below, we are creating summary statistics for the FinnGen data release 11:

View summary statistics

After generating the summary statistics, click the View latest result button on the right side of the Generate button to see the summary statistics.

Below are summary statistics for the Demographics Age and Demographics Gender features in FinnGen data release 11: